Search results for "Ductus venosus"

Transient hepatic nodular lesions associated with patent ductus venosus in preterm infants.

2010

We report on two cases of low-birth-weight preterm infants with patent ductus venosus associated with hepatic hypoechoic lesions of the fourth segment in an otherwise normal liver. Although tumorlike hepatic lesions have been previously reported in association with portosystemic shunts in children and adults, they were never described in preterm infants during physiological patency of ductus venosus. In our patients, hepatic lesions disappeared shortly after the spontaneous ductus closure. Physiopathologic interactions are discussed regarding altered portal blood supply caused by ductus venosus shunt.

Cardiac output following fetoscopic coagulation of major placental vessels in fetal sheep.

2008

Objectives To measure changes in cardiac output (CO) after partial cord occlusion in fetal sheep in order to investigate pathophysiological fetal adaptation mechanisms in a simulated acute placental insufficiency model under standardized conditions, with the aim of finding relevant methods for monitoring human fetuses during stress situations. Methods We used minimally invasive, percutaneous endoscopic techniques to close umbilical vessels in mid-gestational fetal sheep. Placental blood flow was reduced by preferentially closing first arterial and then the concomitant venous umbilical vessels within a short time interval. The investigations were carried out on 11 pregnant ewes at a median g…

Prenatally detected double trisomy: Klinefelter and Down syndrome

2006

Double trisomies are a rare occurrence. We report the first case of a Down and Klinefelter's syndrome (48,XXY,+21) in a fetus that was prenatally diagnosed during the 15th week of pregnancy. Even though the nasal bone was present, and the color-Doppler study of the ductus venosus and the nuchal thickness were normal, the maternal serum test results indicated an increased risk of Down syndrome and consequentially a genetic amniocentesis was performed. A 48,XXY,+21 karyotype was observed and the patient decided to terminate the pregnancy. In this case, we did not find the typical ultrasound (US) signs that would have led us to the chromosomopathy; furthermore, we emphasize the advantages of u…

�ber die Struktur und den Verschlussmechanismus Des ductus venosus

1965

Das Gefasrohr des Ductus venosus schliest nur geringe Mengen der glatten Muskulatur ein. Ein muskularer Sphinkter ist an seinem Abgang nicht vorhanden. Auch andere vorgebildete Strukturen, z. B. die im Schrifttum gelegentlich erwahnten „Lippenbildungen“, die den Ductusabgang postnatal sofort verschliesen sollen, liegen nicht vor. Die postnatale funktionelle Ausschaltung des Ductus venosus ist Folge des Druckabfalles im portalen Sinus (Recessus umbilicalis) und beruht im Wesentlichen auf der Retraktion und Engstellung seines Abganges, dessen lichte Weite vom Gefasinnendruck in hohem Mase abhangig ist. Die Retraktion des Ductusabganges wird wahrscheinlich durch die muskularen Elemente geforde…

Sildenafil citrate improves perinatal outcome in fetuses from pre-eclamptic rats

2012

Please cite this paper as: Herraiz S, Pellicer B., Serra V, Cauli O, Cortijo J, Felipo V, Pellicer A. Sildenafil citrate improves perinatal outcome in fetuses from pre-eclamptic rats. BJOG 2012;119:1394–1402. Objective  To evaluate perinatal outcome after sildenafil citrate (SC) administration at the onset of pregnancy in a rat pre-eclampsia model. Design  In vivo animal experimental study. Setting  Fundacion IVI-Instituto Universitario IVI, Valencia, Spain. Sample Control and pre-eclampsia-induced pregnant Wistar rats exposed to chronic SC administration. Methods  We evaluated the use of SC, which was tested as a potential therapeutic tool to maintain vasodilatation in complicated pregnanc…

OC005: Ultrasound bioeffects: Quantification of cellular damage in animal fetal liver after use of Doppler pulse to measure ductus venosus

2008

OC133: Natriuretic peptide levels in IUGR fetuses with absent and reversed enddiastolic flow of the umbilical artery in relation to ductus venosus fl…

2003

Abnormalities of the umbilico-portal venous system in Down syndrome: A report of two new patients

2003

Congenital anomalies of the umbilical and portal venous system are rare vascular malformations which are often associated with anomalies of the heart and gastrointestinal tract. Association with chromosomal disorders has been sporadically reported. We now report on two patients with trisomy 21 and congenital anomalies of the umbilico-portal system. A male fetus showed absence of the intrahepatic portal vein (PV) and ductus venosus with a direct communication between portal sinus and inferior vena cava exhibiting an umbilicosystemic total shunt during the fetal life and a portosystemic total shunt after birth. A female infant showed absence of the intrahepatic PV and a total portocaval shunt…

Haemodynamic effects of long-term administration of sildenafil in normotensive pregnant and non-pregnant rats

2011

Please cite this paper as: Pellicer B, Herraiz S, Cauli O, Rodrigo R, Asensi M, Cortijo J, Serra V, Morcillo E, Felipo V, Simon C, Pellicer A. Haemodynamic effects of long-term administration of sildenafil in normotensive pregnant and non-pregnant rats. BJOG 2011;118:615–623. Objective  To determine the effects of chronic administration of sildenafil citrateon healthy pregnant rats. Design In vivo animal experimental study. Setting  Fundacion IVI–Instituto Universitario IVI, Valencia, Spain. Sample  Pregnant and non-pregnant Wistarrats exposed to chronic administration of sildenafil. Methods  Placental cross-barrier and feto-maternal relationship levels, maternal blood pressure, and haemody…

Dilation of the ductus venosus by stent implantation increases placental blood perfusion in fetal sheep.

2006

The reduction of resistance to flow in the ductus venous (DV) and a decrease of blood supply to the liver serve for the survival of the fetus during hypoxia. The present study investigated the influence of the increased diameter of the DV on placental blood perfusion.In 15 ewes with twin pregnancies at gestational ages of 117 +/- 4 days, a stent (4 or 5 mm) was placed into the DV of 1 twin (DV(stent) group) under ultrasound guidance. Blood flow rates in the umbilical vein (UV) and DV of both fetuses were measured using Doppler ultrasound. Eight pairs of twin fetuses were included for the final analysis.The dilatation of the DV increased the blood flow volume rate passed through the DV from …